50 Cent has had more success as a producer than an actor.
But he does have an acting career of some note, and during his stop on Jalen Rose's podcast, 50 was asked if he'd every do a romantic comedy.
Fif said he would and had a particular target for his co-star.
"Nicki Minaj would be fun to be in a romantic comedy with," said Fif. "I kinda understand her a little bit more than the other people. I mean, she does sh*t. She's tougher and being like this. But she's being an asshole because she's telling you you're not going to take advantage of her."
50 Cent is a known method actor, famously losing more than 50 pounds for his role in the movie Tough.
So that would probably mean he would try to smash in real life.